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Am J Health-Syst Pharm

The neuroprotective effect of exendin-4 was found to be independent of the glucose-increasing effect, whereas related to increasing the levels of cAMP and reducing oxidative stress and the inflammatory response (83)

All of three dual agonist peptides, tirzepatide, MAR709 and CY-5, have a C-terminal same as exenatide but no convincing reasons have been put forward and its use is more likely an inertia from MAR709

Exploring potential associations between GLP-1RAs and depressive disorders: a pharmacovigilance study based on FAERS and VigiBase data

Pedditzi E, Peters R, Beckett N

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