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Semaglutide Surge Associated With Spike in Poison Control Calls Poison control calls surged after the popular weight-loss drug gained FDA approval

However, its future trajectory is far from linear as many uncertainties remain, e.g., acceptance of obesity as a chronic disease, budget impact faced by payers and health systems willingness and ability to pay, the readout of further cardiovascular outcomes trials after the high profile results of 2023s SELECT trial for Wegovy, or new entrants challenging first generation therapies with alternative mechanisms of action (MoA) to address shortcomings such as gastrointestinal tolerability, current drugs being injectables, or the durability and quality of weight loss which distinguishes between fat and lean body mass

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Category: Clinical Trials & Real-World EvidenceWritten and Reviewed By: Pharmacally Medical News DeskAt European Society of Cardiology Congress 2025 in Madrid happening between August 29 to 1 September 2025, Novo Nordisk reported that Wegovy (semaglutide 2.4 mg) was linked to a 57% lower risk of heart attack, stroke, or death compared with tirzepatide in people

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