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Description
What the 2025 Gastroenterology Metaanalysis Found The systematic review and metaanalysis (DOI: 10.1053/j.gastro.2025.06.003) evaluated safety outcomes across randomized trials and realworld studies of GLP1 RAs

Safety screening layer (contraindications screen + red flag symptom screen with structured notes fields)
We propose that these changes in monotreme GLP-1 are the result of conflicting function of this peptide in metabolic control and venom

Results After weighting, 24817 adults used a GLP-1 receptor agonist (mean age 59.9 years

The FDA states it is GRAS (generally recognized as safe)

Reports of Ozempic mouth gum inflammation, tooth decay, and bad breath are emerging among people using GLP-1 drugs.
