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Impact of Semaglutide on High-Sensitivity C-Reactive Protein: Exploratory Patient-Level Analyses of SUSTAIN and PIONEER Trials

Mice were administered 0.5 mL of semi-liquid by oral gavage, and GE was subsequently assessed

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Chronic daily administration of cotadutide over 27 days in obese mice was associated with food intake reduction, decreased adiposity, improved fasting glucose, and increased energy expenditure

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However, further research is warranted to develop comprehensive, evidence-based guidelines that fully harness this synergy, maximising therapeutic benefits while minimising associated risks