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It is worth mentioning that most of the reasons could be demystified with proper diabetes education and with the new, easier-to-use and painless devices to deliver insulin and monitor blood glucose

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Higher-risk patients have active symptoms, recent dose escalation, high-dose therapy with symptoms, baseline motility disorder, or major aspiration-risk features

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Finally, it is worth mentioning that flatulence may occasionally appear, although studies reporting its frequency are lacking

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The AST:ALT ratio helps identify causes

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Recent large-scale cardiovascular outcome trials have provided additional support for the safety of GLP-1 RAs

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