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Retatrutide is not approved by Health Canada or the FDA for any indication

An association between dipeptidyl peptidase-4 (DPP-4) inhibitor treatment and heart failure has been observed in cardiovascular outcomes trials for two other members of the DPP-4 inhibitor class

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These are powerful medications that require careful consideration and monitoring

American College of Cardiology Clinical Trials Summary

Individuals using semaglutide have reported a notable reduction in their insulin requirements, with many able to decrease or eliminate their daily doses