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Some of the dual and triple agonists have already shown initial successes in clinical trials, although the molecular mechanisms underlying their multiplexed pharmacology remain elusive

GLP-1/GIP Therapy Discontinuation: Why the How Matters One of the most-discussed challenges with GLP-1/GIP agonists such as tirzepatide (Mounjaro) is weight regain after stopping therapy

We now have two FDA-approved drugs for MASLD/MASH: Resmetirom (oral, THR- agonist) Semaglutide (weekly SC, GLP-1 RA) side-by-side comparison, courtesy of @rabataller #MASLD #MASH #FattyLiver @_ILTS_ @EASLedu @AASLDtweets @novonordisk

In recent years, GLP-1 medications have taken the health and wellness world by storm, offering hope to millions struggling with weight loss and metabolic health