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Additionally, sclerostin levels were significantly higher in children and lower in adults with PWS compared to controls, indicating that RANK-L, OPG, and sclerostin may play a crucial role in regulating bone turnover in individuals with PWS
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Animal studies suggest that receptor sensitivity can recover after a period of reduced stimulation, but the timeline varies considerably
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doi: 10.1111/j.1463-1326.2009.01155.x
