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Description
Without adequate protein (and ideally some form of resistance training), the body can lose lean mass as well

Pilla, S

Walter Chan

53 Generally, the reported K m of PARP1 and CD38 for NAD + are lower than those of the sirtuins, suggesting that elevated activation of PARP1 or CD38 may limit endogenous SIRT activation by reducing NAD + content

Important safety considerations include risk of pancreatitis (persistent severe abdominal pain may be a warning sign), gallbladder disease, and dehydration
Those who are pregnant, breastfeeding, or have active cancer should avoid NAD+ therapy
