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Their neglect reflects historical limitations rather than biological inadequacy

2025 Regulatory Status and What Happens Next Retatrutide is currently investigational and not FDA-approved

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NCT04255433) is expected to provide definitive answers on the impact of tirzepatide on cardiovascular disease compared with dulaglutide, a long-acting GLP-1 RA that has been shown to be cardioprotective in individuals with type 2 diabetes at increased cardiovascular risk [31]