side effects to tirzepatide Comparative safety and of semaglutide and tirzepatide: Implications for clinical decision-making in obesity management Tirzepatide vs. Retatrutide: Key Differences

for example, there were fewer injection-site reactions with once-weekly compared with twice-daily exenatide (42)

Nausea affects approximately 28% of users at higher doses, while diarrhea impacts around 24%

How These Results Compare to Other Weight Loss Medicines Retatrutide's 24.2% mean weight loss at 48 weeks exceeds phase 3 data for semaglutide 2.4 mg (~14.9% at 68 weeks) and is comparable to tirzepatide 15 mg (~22.5% at 72 weeks), though no direct head-to-head trials have been conducted

Sep 23 2020;12(10)doi:10.3390/nu12102909 Diederichsen ACP, Lindholt JS, Moller S, et al

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