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Most GLP-1 users level out between 12-18% total loss, and the rate of change slows significantly

Diabetes, Obesity and Metabolism, 22 (9), 1772-1780

Long-term effects have not been studied in humans or even in animals beyond short-term protocols

The composition according to any one of the preceding embodiments, wherein the isotonic agent is propylene glycol

It is helpful to see what the drug does in the body

These findings stand in contrast to prior data, showing no significant risk of thyroid cancer with semaglutide use, suggesting that differences in study design, population, and possibly the formulations of GLP-1 RAs used could contribute to these varying outcomes