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As reported by the Centers for Disease Control and Prevention (CDC), respiratory depression is the direct cause of death in nearly 50% of opioid-related overdoses

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If multiple publications were identified for the same patient population, location and setting, intervention details, baseline data and study data, such studies were linked and extracted as a single reference

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"The problem I see is that it's been delivered faster and louder through algorithms that know exactly where our vulnerabilities are, Dr Raykos said

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Fatigue: Some individuals may feel more tired than usual during this initial adjustment phase

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Administration of glucose or fat directly into the duodenum of such rodents rapidly stimulates L-cell GLP-1 secretion, with a magnitude comparable to that occurring when nutrients are directly placed into the ileum [289,320]

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