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Hence, in 2022, glucose-lowering efficacy and proven cardiovascular effects were important for the strong positioning of semaglutide, dulaglutide and tirzepatide in guidelines on the management of hyperglycaemia in type 2 diabetes [33], and a similar strong positioning of incretin therapy was seen in guidelines on primary care [39]

Without benzyl alcohol, reconstituted peptide solution would need to be used within 24 hours (the standard for sterile water for injection)

In the UK, Wegovy is already licensed for weight management and cardiovascular risk reduction, but not yet approved for MASH

This treatment has been long recognised as an effective treatment for managing type 2 diabetes, but has been FDA-approved as a medical weight loss treatment in 2021

Physician-Led, On-Site Care: GLP1 agonist therapy is provided in a physician-directed medspa where in-person assessments, dose adjustments, and supportive lifestyle recommendations are delivered by medically trained clinicians

Why the gap