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[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Forecasting trial milestones: a predictive analysis for early termination of the SOUL study

At the very least, we have laid a pathway for the prolonged release of therapeutic GLP-1based anti-diabetic and anti-obesity treatments that could have beneficial impact on type 2 diabetes management and, perhaps, other conditions as well, Appel said in the same statement

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Summary: Ispaghula (psyllium) husk may modestly increase endogenous GLP-1 secretion through delayed gastric emptying and colonic fermentation, though the clinical significance remains uncertain
Without that, the timeline to results often stretches out

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