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Individualization is Key: The ADA strongly advocates tailoring HbA1c goals based on: Duration of diabetes Risk of hypoglycemia Life expectancy Comorbidities (cardiovascular disease, CKD) Patient preference and treatment burden Beyond HbA1c: Modern diabetes care increasingly integrates Continuous Glucose Monitoring (CGM) metrics such as Time in Range (TIR) alongside HbA1c

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OBJECTIVES: Pediatric Metabolic-dysfunction Associated Steatotic Liver Disease (MASLD), formerly known as Non-Alcoholic Fatty Liver Disease (NAFLD) is characterized by hepatic steatosis with at least one risk factor indicative of cardiometabolic dysfunction

We break down the key differences in mechanism, evidence base, side effects, and who each one is actually relevant for.