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Description

Structural analysis of the dual agonism at GLP-1R and GCGR

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Assessing proportionality in the proportional odds model for ordinal logistic regression

26 Unlike natural GLP-1, which is rapidly broken down by DPP-4, GLP-1RAs are structurally modified to resist degradation by DPP-4

Imaging Preferred modality : CT abdomen with oral or IV contrast Alternative modalities MRI abdomen Magnetic resonance enterography Findings Multiple round or ovoid, thin-walled outpouchings Usually located on the mesenteric border No plicae circulares May contain air-fluid level Laparotomy Gold standard Not the preferred modality as it is invasive Diagnosis of bleeding from small bowel diverticula Small bowel endoscopy (e.g., capsule or double-balloon enteroscopy): high yield Angiography (e.g., CT angiography): for brisk bleeding Nuclear medicine scan: for slower bleeding See also "Approach to suspected small bowel bleeding." Avoid oral contrast in patients with an acute GI bleed as it may interfere with therapeutic endoscopy or angiography