glp-1 afib receptor agonists and myocardial metabolism in atrial fibrillation Impact of GLP-1 Receptor Agonist

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Group one included patients with moderate PAD who were started on GLP-1 RAs, and group two included patients with moderate PAD who were not started on GLP-1 RAs. At one year, patients with moderate PAD who were started on GLP-1 RAs had fewer major adverse limb events (MALE) (0.8% vs 1.5%), major adverse cardiac events (MACE) (25.4% vs 29.3%), and decreased risk of hospitalizations (17.9 vs 26.8%)

By adding additional indications, such as cardiovascular (CV) risk for Wegovy, and obstructive sleep apnea for Zepbound, they have increased their value proposition and bargaining power with payers

When they stop, the behaviors and risks that led them there often return