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(2.1) Prior to initiation, assess renal function with estimated glomerular filtration rate (eGFR) (2.2) Do not use in patients with eGFR below 30 mL/min/1.73 m2

January 2010

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However, when insulin sensitivity is lowknown as insulin resistanceglucose builds up in the bloodstream, increasing the risk of type 2 diabetes, obesity, and other metabolic disorders