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RNA immunoprecipitation (IP) and quantitative PCR JK5366 and JK5574 were raised at 15C until they developed germline tumors as young adults (see tumor assay above)

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The synthetic GLP-1 receptor agonists mimic this endogenous hormone but are modified to resist rapid enzymatic breakdown by dipeptidyl peptidase-4 (DPP-4), thereby extending their duration of action

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Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites
