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Common side effects of Metformin tablets include diarrhea, nausea, and upset stomach

As of 2022, GLP-1RAs have been recommended as first-line treatments, along with SGLT-2 inhibitors, for patients with T2DM and cardiovascular disease in American Diabetes Associations Standards of Medical Care in Diabetes (248, 249)

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One of the primary effects of GLP-1 is its ability to reduce hunger and increase feelings of satiety, which is particularly noticeable in the early stages of treatment