glp 1 drugs and fibromyalgia Weight Loss Injections for Chronic Pain GLP-1 Medications May Reduce Pain

New research suggests the amount of weight patients lose after starting these medications could strongly influence their future risk of serious obesity-related diseases

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10.1111/acer.14437 12 DoutonJ

In the adipose tissue of GLP-1-treated ob/ob mice expressing recombinant adenovirus, for instance, GLP-1RA has been shown to decrease the production of TNF-, IL-6, and IL-1, all of which are significant mediators of inflammation

Over 72 weeks, participants without type 2 diabetes achieved the following weight loss results : 5 mg dose: 16.0% average body weight reduction 10 mg dose: 21.4% average body weight reduction 15 mg dose: 22.5% average body weight reduction Placebo: 2.4% average body weight reduction At the highest dose, 92.7% of participants achieved at least 5% weight loss, 84.4% achieved at least 10%, 73.6% achieved at least 15%, 56.1% achieved at least 20%, and 38.7% achieved at least 25% weight loss

Ozempic is the brand name for semaglutide