gip and glp-1 agonist The Effects of Dual GLP-1/GIP Receptor Agonism on Glucagon Secretion—A Review GIP Receptor Agonism Attenuates GLP-1
Description
Continuous lifestyle support is recommended to reduce weight regain after discontinuation of GLP-1 receptor agonist therapy

This process was repeated 10,000 times to estimate the median and 95 % confidence interval (CIs) of the drug effects at each time point for each subgroup

Discontinuing Glucagon-Like Peptide-1 Receptor Agonists and Body Habitus: A Systematic Review and Meta-Analysis

2017;9:eaan0972 Ast J, Arvaniti A, Fine N, Nasteska D, Ashford FB, Stamataki Z, et al

Preclinical studies have indicated that GLP1RAs, such as tirzepatide, may directly impact the vasculature by enhancing endothelial function and decreasing inflammation, which are important in preventing atherosclerosis[30]
Suppression of neuroinflammation, shifting microglia and astrocytes toward neuroprotective phenotypes
