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And this is happening against geopolitical and post-COVID supply chain challenges generally within the pharma industry. However, Barry sees some hope in alleviating the problem in the manufacturing sector, as drugmakers are pouring money into boosting their capacity to make GLP-1s

The most common ones are nausea, diarrhea, constipation, vomiting, and decreased appetitewhich can occur with semaglutide and tirzepatide, too

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Understanding the intersection of these two approaches can provide insights into effective obesity management strategies

Weight typically levels off after the first year, though individuals may continue seeing slow improvements with regular use

Matthew Hayes, a nutritional neuroscientist at the University of Pennsylvania, who has studied GLP-1 and other gut hormones since 2006, explains that these drugs work partly because they slow digestion and modulate glucose levels