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showed that empagliflozin administration in prediabetic rats has an important systemic metabolic effect on alterations in substrate utilization, diverting from glucose oxidation to fatty acid oxidation and increasing ketone body use

If you find you need additional support, your provider might suggest transitioning to more affordable oral medications, such as metformin, naltrexone/bupropion, or orlistat, to help maintain your progress

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[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Buysschaert M., Tennstedt D., Preumont V

While this research wasnt focused on microdosing specifically, it helps explain why some patients report improvements in pain and fatigue at lower doses