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CV Protection in the EMPA-REG OUTCOME trial: a thrifty substrate hypothesis
Their liraglutide study [36], showed similar findings, with a reduced papilledema risk at 3 months (RR ~ 0.33) that persisted at 24 months (RR ~ 0.52)
Calles-Escandon J, Koch KL, Hasler WL, Van Natta ML, Pasricha PJ, Tonascia J, et al
For example, removal of excessive sympathetic activation in obese subjects with the ganglionic blocker, trimethaphan resulted in an improvement in insulin sensitivity during hyperinsulinemic-euglycemic clamps
20 of those made it into the United States
PloS One
