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TL;DR Zepbound (tirzepatide) is an FDA-approved injectable medication that works by activating two hormone receptors-GLP-1 and GIP-simultaneously, making it the first dual-agonist weight loss drug

Dipeptidyl peptidase 4 inhibitor sitagliptin protected against dextran sulfate sodium-induced experimental colitis by potentiating the action of GLP-2

Side effects on Wegovy that are likely to recur on Zepbound

Cost and insurance The cost of phentermine and combination medications can vary