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Orlistat Orlistat inhibits pancreatic lipase and thereby reduces the absorption of fatty acids in the intestines, causing an energy deficit of approximately 300 kcal/day
Interestingly, DPP-4 inhibition increases circulating endothelial progenitor cells, likely targeting the chemokine stromal-cell-derived factor 1, an important protective system [61]

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coli have been reported to activate host intestinal defense factors and inhibit the growth of other harmful gut bacteria, and their roles are expected to be diverse 12,13

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