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This meta-analysis evaluates their effects on mortality and hospitalization in HFpEF

Fatigue emerging after months of feeling fine may indicate a new issue unrelated to initial treatment adjustment

These substances may increase the risk of irritation, unexpected reactions, or other side effects when the medication is used

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They stimulate glucose-dependent insulin secretion from pancreatic beta cells

Weight loss timeline and realistic expectations Setting realistic expectations prevents disappointment and premature discontinuation