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SURMOUNT-5 Head-to-Head In 2025, Eli Lilly published the SURMOUNT-5 trial directly comparing tirzepatide (15 mg) and semaglutide (2.4 mg) in adults with obesity over 72 weeks

Subjects were identified by use of antipsychotic (quetiapine, risperidone, paliperidone, olanzapine, clozapine) with concomitant use of monotherapy or combination therapy

Weight gain on the scale This is the most common source of confusion

He reads labs, thinks in systems, and treats patients the way he'd want to be treated

Rubber band ligation is the best treatment modality

Available GLP-1s include semaglutide (Ozempic/Wegovy active ingredient) and tirzepatide (Mounjaro/Zepbound active ingredient, also targets GIP receptors)