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If drugs to mitigate nausea (or other GI AEs) are needed for over a month when the maintenance GLP-1 RA dose has been reached, a dose reduction should be considered for the patient to tolerate the drug with no need for pharmacological support [35]

Common Side Effects Many patients report mild to moderate symptoms when they first start or when they increase their dose
I never recommend supplements that contain proprietary blends, for several reasons: First of all, we have no way of knowing if the product contains effective doses of their active ingredients

Patients: A total of 9650 adult patients with established CV disease without CKD (56.7%), CKD only (13%), or both CV disease and CKD (27%) were randomized 1:1 to receive semaglutide tablets 14 mg (n=4825) or placebo (n=4825) once daily, both in addition to standard-of-care treatments for glycemic control and CV risk factors including blood pressure medication, lipid-lowering agents, and antiplatelet/anticoagulant therapy
F., Ozenne B., Hansen H

Moreover, a large proportion of our patients were on newer GLP-based therapies, such as semaglutide and tirzepatide