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The 6.0 mg dose showed slightly less MASH resolution than 4.8 mg, likely because higher dropout rates from side effects affected the intent-to-treat analysis

In the Phase 2 trial published in the New England Journal of Medicine, participants receiving the highest dose of retatrutide achieved an average body weight reduction of 24.2% over 48 weeks

Broad Scope: The drugs studied included liraglutide, semaglutide, dulaglutide, exenatide, lixisenatide, and albiglutide

Tirzepatide e sicurezza: monitoraggio, esami necessari e follow-up clinico La sicurezza della tirzepatide passa da un monitoraggio attivo nei primi mesi

doi: 10.1089/dia.2005.7.467

This trial evidence is why many endocrinologists consider semaglutide a first-line agent for type 2 diabetes when weight loss and glucose control are both desired