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Although metabolic syndromes and obesity share some of the typical hallmarks, it is essential to acknowledge that lifestyle choices, diet, and genetics may influence the development of these dysfunctions

Always consult your pharmacist or doctor before starting anti-sickness medication to review potential drug interactions and appropriate duration

For example, DHEA(S) concentrations often decrease non-specifically with chronic illness and this may confound studies examining differences in DHEA(S) concentrations in clinical populations, since the lowered hormone concentrations may reflect chronic medical illness, rather than having diagnostic specificity or direct pathophysiologic significance [157]

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Published analyses of the STEP trials (Wilding et al., NEJM 2021

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