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These effects were accompanied by increased intratumoral CD4+ T-cell and natural killer (NK) cell frequencies, a shift of CD8+ and conventional CD4+ T cells toward a memory-like phenotype, reduced regulatory T-cell abundance, and improved antigen-presenting cell-associated immune features (111)

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In some cases, slowed intestinal motility may lead to small intestinal bacterial overgrowth (SIBO), further contributing to bloating and gas