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The most common side effects associated with GLP-1 agonists include appetite loss, nausea, vomiting, and diarrhea, which are often more pronounced when starting the medication or increasing the dosage (4)(10)(23)

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Therefore, clinical claims should focus on improving cardiometabolic risk factors and metabolic substrates rather than prematurely extrapolating MACE reduction data from general obesity populations

Never use a GLP-1 medication beyond its expiry date or recommended in-use period , even if it has been continuously refrigerated, as the active ingredient may degrade and lose potency