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With so many potential benefits, its understandable to have questions about GLP-1 drugs, including where they came from and how they work

Miller: Yeah, I'd avoid doing that

Numbers 2 and 3 are responsible for weight loss, as shown below, circled in green

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doi:10.1210/jc.2018-00199 Lingvay I, Desouza CV, Lalic KS, et al

Findings of the prespecified analysis of the trial, published in The Lancet, suggest that semaglutide and possibly other glucagon-like peptide-1 receptor agonists (GLP-1Ras) should be reconceptualised as disease-modifying treatments rather than solely medications for glycaemic control or weight loss, the studys authors have suggested