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The FDAs decision was largely based on data from the SOUL trial, which included data from more than 9,000 patients who were randomized to oral Semaglutide or a placebo, & all patients had type 2 diabetes in addition to known ASCVD , CKD or both

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Both GLP-1 and GLP-1/GIP receptor agonists have different mechanisms and dose-response profiles

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Natural GLP1 plays a crucial role in regulating appetite, blood sugar, and overall metabolic health, yet many seek ways to enhance its levels without relying on medication

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