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The purpose of this review is to summarise the physiological effects as well as the therapeutic implications of the gut hormones glucagon-like peptide-1 (GLP-1), oxyntomodulin, peptide YY (PYY), and glucose-dependent insulinotropic peptide (GIP) in the treatment of obesity and type 2 diabetes

BA are, therefore, involved in the maintenance of gut barrier integrity, gene expression, metabolic homeostasis, and microbiota profile and function

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When Trova Wine and Market in Dallas shut its doors last month after nearly five years in business, owner Michelle Bonds pointed to an unexpected reason for closure: GLP-1 weight

22, 2025, when the U.S Food and Drug Administration (FDA) approved oral Wegovy by Novo Nordisk as the first daily, oral GLP-1 pill for weight management.

TRANSCEND-T2D-1: Retatrutide in adults with obesity and type 2 diabetes