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Peer-reviewed research published in journals including the New England Journal of Medicine has demonstrated statistically significant weight loss outcomes with semaglutide and tirzepatide in large randomized controlled trials involving thousands of participants tracked over periods of 68 weeks or longer

WMD = 2.30 kg, 95% CI 0.53 to 4.07, P = 0.01, 2 = 0.0%

Published 2020 Apr 3

But they do not know if their BMI qualifies them, which comorbidities count, or whether their insurance will actually cover the prescription even if they meet the clinical criteria

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