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Understanding which medications can be safely continued or should be paused before surgery is key to providing comprehensive and effective care. # # # 2025 AAOS Annual Meeting Disclosure Statement About the AAOS With more than 39,000 members, the American Academy of Orthopaedic Surgeons is the worlds largest medical association of musculoskeletal specialists

they are better interpreted as reassuring for cardiovascular safety when tirzepatide is used to treat coexisting obesity or diabetes in HFrEF rather than as evidence of HFspecific efficacy [49]

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