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Its dual mechanism of action offers a more holistic approach to managing diseases like obesity and diabetes, as opposed to single-receptor agonists that only target one aspect of metabolic control

However, research published in the Annals of Internal Medicine found an important nuance: longer-acting GLP-1 receptor agonists (which includes both tirzepatide and once-weekly semaglutide) were actually associated with lower GERD risk than shorter-acting versions like liraglutide

This overview is not comprehensive

[DOI] [PubMed] [Google Scholar] 232.Kandaswamy R, Sutherland DER

As the mechanisms underlying disease pathology are unveiled, various therapeutics are being repurposed for their use in neuro-ophthalmology