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Drug Interactions: Inform your doctor about any other medications you are taking to avoid possible interactions

In subjects with severe RI, the mean exposure of semaglutide was 22% higher than in subjects with normal renal function, and the 95% confidence interval (1.021.47) for the ratio exceeded the pre-specified limits (0.701.43)

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Whereas GLP-1 acts in the periphery to inhibit glucagon secretion and stimulate insulin release, it also acts in the central nervous system to ...

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