glp 1 receptor agonists incretin mimetics Clinical Focus on GLP-1 in Type 2 Diabetes Mellitus Glucagon-like Peptide-1 (GLP-1) AGONIST -

Description

Historically, natural products have demonstrated considerable potential as a source of drug discovery with the help of their chemical structure and recent endeavors on this field have focused on investigating the GLP-1 activating capabilities of various products which are naturally sourced from traditionally employed medicinal flora or nutritional origins

J Biol Chem 263: 1347513478, 1988

(ePub ahead of print)

With medical supervision both can be appropriate complementary additions without supervision the combined effect requires monitoring

"Beneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metformin"