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Well, one thing that makes diabetes stand out from other diseases where that frequent urination is a symptom is that diabetics urine is almost always high in sugar

placebo A 2025 study showed that adults with obesity who took a higher dose of Wegovy (7.2 mg) lost around 21% of their body weight over 72 weeks

These drugs, however, are not being developed for PA (a small market, though arguable point) but in hypertension and in diabetic nephropathy, with multiple companies and molecules in phase 3 development: Baxdrostat (Astra Zeneca) in hypertension (Phase 2 RCT: Freeman et al, NEJM 2022

Multifactorial diseases of the heart, kidneys, lungs, and liver and incident cancer: epidemiology and shared mechanisms

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During titration, Michael experienced significant nausea during weeks 2-4 which his provider managed by slowing dose escalation staying at the starting dose for 6 weeks instead of the standard 4