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Lupus, Inflammation, and Weight Gain: The Connection Lupus-related inflammation drives production of pro-inflammatory cytokines including TNF-alpha, IL-6, and IL-10, which directly increase appetite and reduce energy expenditure through hypothalamic signaling pathways
Wharton et al., 2023) which persisted for up to 2 years (Wharton et al., 2023)
And that one, Foundayo, is not a peptide, but a small molecule that also hits the GLP-1 receptor
doi: 10.1056/NEJMoa2407379
