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Thus, optimizing GLP-1 therapies requires an integrated approach that supports adequate nutrition and physical activity, addresses body composition changes, and proactively manages GI side effects to maximize adherence and long-term clinical benefit

All of these things are important

MHRA-approved options for weight management in the UK include semaglutide 2.4 mg (Wegovy), tirzepatide (Mounjaro), orlistat, and naltrexone/bupropion (Mysimba), with eligibility criteria varying by treatment

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