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Biological function of the BBB The BBB is a physical and biochemical barrier that precisely regulates environmental homeostasis in brain tissue

Co-infusion of GLP-1 and GCG has been shown to reduce glucagon-induced hyperglycemia, lower blood glucose levels, suppress food intake, and enhance energy expenditure in both diabetic obese mice and healthy human volunteers [78]

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- Phase 3b SOUL trial: Rybelsus reduced major adverse cardiovascular events (MACE CV death, heart attack, stroke) by 14% vs

Dudley LM, Saluja S, Stevenson RJ, Francis HM, Case TI

Treatment arm name denotes pre-dose and post-dose fasting period