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Glucagon-like peptide-1 (GLP-1) receptor agonists, including semaglutide ( Ozempic or Wegovy ), mimic a natural hormone that suppresses appetite, regulates insulin and blood sugar and slows emptying of the stomach

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Langer and colleagues, in a March 2026 Cell Reports Medicine paper combining four preclinical mouse studies with a proof-of-concept clinical trial, performed what may be the first published direct measurement of muscle function alongside body composition in patients on a GLP-1 RA