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Menstrual cycles, hormonal profile, and insulin resistance also improved beyond the effect of metformin alone.This case highlights the potential of exenatide to provide dual therapeutic benefits in IIH and PCOS, acting through direct receptor-mediated pathways to reduce ICP, improve headaches, and restore ovulatory cycles, and indirectly through the reduction of central obesity

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4 PK strategy Rybelsus: steady exposure for glycaemic control Oral Wegovy: sustained appetite suppression Higher total exposure, with carefully controlled peaks 5 Regulatory reality Higher dose + new indication = new clinical package (and often a re-optimized formulation) This is treated as a new medicine, not a relabel.

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