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Protein intake deserves special attention

Phase-level cost benchmarks from published literature (primarily Sofpromed and Johns Hopkins analyses) provide more useful guidance: Phase I trials cost between USD 4 million and USD 22 million on average, with the wide range reflecting study design complexity PK/PD characterization, SAD/MAD designs, drug-drug interaction studies, special populations studies

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Light activity, even a 20-minute walk, can improve energy more than resting